An Integrated Bioinformatics Analysis Repurposes an Antihelminthic Drug Niclosamide for Treating HMGA2-Overexpressing Human Colorectal Cancer

Aberrant overexpression of high mobility group AT-hook 2 (HMGA2) is frequently found in cancers and HMGA2 has been considered an anticancer therapeutic target. In this study, a pan-cancer genomics survey based on Cancer Cell Line Encyclopedia (CCLE) and The Cancer Genome Atlas (TCGA) data indicated...

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Detalles Bibliográficos
Autores principales: Leung, Stephen Wan, Chou, Chia-Jung, Huang, Tsui-Chin, Yang, Pei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826424/
https://www.ncbi.nlm.nih.gov/pubmed/31581665
http://dx.doi.org/10.3390/cancers11101482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826424/
https://www.ncbi.nlm.nih.gov/pubmed/31581665
http://dx.doi.org/10.3390/cancers11101482

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