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Family C G-Protein-Coupled Receptors in Alzheimer’s Disease and Therapeutic Implications

Alzheimer’s disease (AD), particularly its sporadic or late-onset form (SAD/LOAD), is the most prevalent (96–98% of cases) neurodegenerative dementia in aged people. AD’s neuropathology hallmarks are intrabrain accumulation of amyloid-β peptides (Aβs) and of hyperphosphorylated Tau (p-Tau) proteins,...

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Detalles Bibliográficos
Autores principales: Dal Prà, Ilaria, Armato, Ubaldo, Chiarini, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826475/
https://www.ncbi.nlm.nih.gov/pubmed/31719824
http://dx.doi.org/10.3389/fphar.2019.01282