N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil Targeting FBXW7 Tumor Suppressor

N6-isopentenyladenosine has been shown to exert potent in vitro antitumor activity on different human cancers, including colorectal cancer. Although some potential biochemical targets have been identified, its precise mechanism of action remains unclear. We found that N6-isopentenyladenosine affects...

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Detalles Bibliográficos
Autores principales: Fiore, Donatella, Piscopo, Chiara, Proto, Maria Chiara, Vasaturo, Michele, Dal Piaz, Fabrizio, Fusco, Bruno Marcello, Pagano, Cristina, Laezza, Chiara, Bifulco, Maurizio, Gazzerro, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826543/
https://www.ncbi.nlm.nih.gov/pubmed/31569395
http://dx.doi.org/10.3390/cancers11101456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826543/
https://www.ncbi.nlm.nih.gov/pubmed/31569395
http://dx.doi.org/10.3390/cancers11101456

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