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N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil Targeting FBXW7 Tumor Suppressor
N6-isopentenyladenosine has been shown to exert potent in vitro antitumor activity on different human cancers, including colorectal cancer. Although some potential biochemical targets have been identified, its precise mechanism of action remains unclear. We found that N6-isopentenyladenosine affects...
Autores principales: | Fiore, Donatella, Piscopo, Chiara, Proto, Maria Chiara, Vasaturo, Michele, Dal Piaz, Fabrizio, Fusco, Bruno Marcello, Pagano, Cristina, Laezza, Chiara, Bifulco, Maurizio, Gazzerro, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826543/ https://www.ncbi.nlm.nih.gov/pubmed/31569395 http://dx.doi.org/10.3390/cancers11101456 |
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