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Prognostic Implication of pAMPK Immunohistochemical Staining by Subcellular Location and Its Association with SMAD Protein Expression in Clear Cell Renal Cell Carcinoma

Although cytoplasmic AMP-activated protein kinase (AMPK) has been known as a tumor-suppressor protein, nuclear AMPK is suggested to support clear cell renal cell carcinoma (ccRCC). In addition, pAMPK interacts with TGF-β/SMAD, which is one of the frequently altered pathways in ccRCC. In this study,...

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Detalles Bibliográficos
Autores principales: Jung, Minsun, Lee, Jeong Hoon, Lee, Cheol, Park, Jeong Hwan, Park, Yu Rang, Moon, Kyung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826619/
https://www.ncbi.nlm.nih.gov/pubmed/31640193
http://dx.doi.org/10.3390/cancers11101602