Targeting G-quadruplexes with Organic Dyes: Chelerythrine–DNA Binding Elucidated by Combining Molecular Modeling and Optical Spectroscopy

The DNA-binding of the natural benzophenanthridine alkaloid chelerythrine (CHE) has been assessed by combining molecular modeling and optical absorption spectroscopy. Specifically, both double-helical (B-DNA) and G-quadruplex sequences—representative of different topologies and possessing biological...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Terenzi, Alessio, Gattuso, Hugo, Spinello, Angelo, Keppler, Bernhard K., Chipot, Christophe, Dehez, François, Barone, Giampaolo, Monari, Antonio
Materyal Türü: Online Makale Metin
Dil:English
Baskı/Yayın Bilgisi: MDPI 2019
Konular:
Article
Online Erişim:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826623/
https://www.ncbi.nlm.nih.gov/pubmed/31658666
http://dx.doi.org/10.3390/antiox8100472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826623/
https://www.ncbi.nlm.nih.gov/pubmed/31658666
http://dx.doi.org/10.3390/antiox8100472

Benzer Materyaller