Identification of a Synergistic Multi-Drug Combination Active in Cancer Cells via the Prevention of Spindle Pole Clustering

A major limitation of clinically used cancer drugs is the lack of specificity resulting in toxicity. To address this, we performed a phenotypically-driven screen to identify optimal multidrug combinations acting with high efficacy and selectivity in clear cell renal cell carcinoma (ccRCC). The searc...

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Detalles Bibliográficos
Autores principales: Weiss, Andrea, Le Roux-Bourdieu, Morgan, Zoetemelk, Marloes, Ramzy, George M., Rausch, Magdalena, Harry, Daniela, Miljkovic-Licina, Marijana, Falamaki, Katayoun, Wehrle-Haller, Bernard, Meraldi, Patrick, Nowak-Sliwinska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826636/
https://www.ncbi.nlm.nih.gov/pubmed/31652588
http://dx.doi.org/10.3390/cancers11101612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826636/
https://www.ncbi.nlm.nih.gov/pubmed/31652588
http://dx.doi.org/10.3390/cancers11101612

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