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Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer

Epithelial mesenchymal transition is a common mechanism leading to metastatic dissemination and cancer progression. In an effort to better understand this process we found an intersection of Nrf2/NLE2F2 (Nrf2), epithelial mesenchymal transition (EMT), and metabolic alterations using multiple in vitr...

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Detalles Bibliográficos
Autores principales: Haley, John A., Ruiz, Christian F., Montal, Emily D., Wang, Daifeng, Haley, John D., Girnun, Geoffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826656/
https://www.ncbi.nlm.nih.gov/pubmed/31581742
http://dx.doi.org/10.3390/cancers11101488