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Detailed Characterization of Immune Cell Infiltrate and Expression of Immune Checkpoint Molecules PD-L1/CTLA-4 and MMR Proteins in Testicular Germ Cell Tumors Disclose Novel Disease Biomarkers

Background: The immune infiltrate plays an important part in testicular germ cell tumors, but it remains scarcely studied. We aimed at thoroughly characterizing the immune infiltrate and expression of immune checkpoints PD-L1/CTLA-4 and mismatch repair (MMR) proteins in these neoplasms, seeking for...

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Detalles Bibliográficos
Autores principales: Lobo, João, Rodrigues, Ângelo, Guimarães, Rita, Cantante, Mariana, Lopes, Paula, Maurício, Joaquina, Oliveira, Jorge, Jerónimo, Carmen, Henrique, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826711/
https://www.ncbi.nlm.nih.gov/pubmed/31614500
http://dx.doi.org/10.3390/cancers11101535