Microsatellite Instability: Diagnosis, Heterogeneity, Discordance, and Clinical Impact in Colorectal Cancer

Tumor DNA mismatch repair (MMR) deficiency testing is important to the identification of Lynch syndrome and decision making regarding adjuvant chemotherapy in stage II colorectal cancer (CRC) and has become an indispensable test in metastatic tumors due to the high efficacy of immune checkpoint inhi...

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Detalles Bibliográficos
Autores principales: Evrard, Camille, Tachon, Gaëlle, Randrian, Violaine, Karayan-Tapon, Lucie, Tougeron, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826728/
https://www.ncbi.nlm.nih.gov/pubmed/31618962
http://dx.doi.org/10.3390/cancers11101567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826728/
https://www.ncbi.nlm.nih.gov/pubmed/31618962
http://dx.doi.org/10.3390/cancers11101567

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