Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility

DNA topoisomerase II (TOP2) plays a critical role in many processes such as replication and transcription, where it resolves DNA structures and relieves torsional stress. Recent evidence demonstrated the association of TOP2 with topologically associated domains (TAD) boundaries and CCCTC-binding fac...

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Detalles Bibliográficos
Autores principales: Atkin, Naomi D., Raimer, Heather M., Wang, Yuh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826763/
https://www.ncbi.nlm.nih.gov/pubmed/31614754
http://dx.doi.org/10.3390/genes10100791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826763/
https://www.ncbi.nlm.nih.gov/pubmed/31614754
http://dx.doi.org/10.3390/genes10100791

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