Analysis of Promoter-Associated Chromatin Interactions Reveals Biologically Relevant Candidate Target Genes at Endometrial Cancer Risk Loci

The identification of target genes at genome-wide association study (GWAS) loci is a major obstacle for GWAS follow-up. To identify candidate target genes at the 16 known endometrial cancer GWAS risk loci, we performed HiChIP chromatin looping analysis of endometrial cell lines. To enrich for enhanc...

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Detalles Bibliográficos
Autores principales: O’Mara, Tracy A., Spurdle, Amanda B., Glubb, Dylan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826789/
https://www.ncbi.nlm.nih.gov/pubmed/31561579
http://dx.doi.org/10.3390/cancers11101440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826789/
https://www.ncbi.nlm.nih.gov/pubmed/31561579
http://dx.doi.org/10.3390/cancers11101440

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