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Anti-Tumor Drug-Loaded Oxygen Nanobubbles for the Degradation of HIF-1α and the Upregulation of Reactive Oxygen Species in Tumor Cells

Hypoxia is a key concern during the treatment of tumors, and hypoxia-inducible factor 1 alpha (HIF-1α) has been associated with increased tumor resistance to therapeutic modalities. In this study, doxorubicin-loaded oxygen nanobubbles (Dox/ONBs) were synthesized, and the effectiveness of drug delive...

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Detalles Bibliográficos
Autores principales: Khan, Muhammad Saad, Hwang, Jangsun, Lee, Kyungwoo, Choi, Yonghyun, Seo, Youngmin, Jeon, Hojeong, Hong, Jong Wook, Choi, Jonghoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826834/
https://www.ncbi.nlm.nih.gov/pubmed/31569523
http://dx.doi.org/10.3390/cancers11101464