The PAK1-Stat3 Signaling Pathway Activates IL-6 Gene Transcription and Human Breast Cancer Stem Cell Formation

Cancer stem cells (CSCs) have unique properties, including self-renewal, differentiation, and chemoresistance. In this study, we found that p21-activated kinase (PAK1) inhibitor (Group I, PAK inhibitor, IPA-3) and inactivator (ivermectin) treatments inhibit cell proliferation and that tumor growth o...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Hyang, Choi, Hack Sun, Kim, Su-Lim, Lee, Dong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826853/
https://www.ncbi.nlm.nih.gov/pubmed/31658701
http://dx.doi.org/10.3390/cancers11101527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826853/
https://www.ncbi.nlm.nih.gov/pubmed/31658701
http://dx.doi.org/10.3390/cancers11101527

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