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Multiple sclerosis disease progression: Contributions from a hypoxia–inflammation cycle

Hypoxia has been associated with multiple sclerosis (MS) and is an important area of research. Hypoxia can exacerbate inflammation via the prolylhydroxylase pathway. Inflammation can also trigger hypoxia by damaging mitochondria and endothelial cells to impair blood flow regulation. We hypothesize t...

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Detalles Bibliográficos
Autores principales: Yang, Runze, Dunn, Jeff F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826859/
https://www.ncbi.nlm.nih.gov/pubmed/30052113
http://dx.doi.org/10.1177/1352458518791683