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Multiple sclerosis disease progression: Contributions from a hypoxia–inflammation cycle
Hypoxia has been associated with multiple sclerosis (MS) and is an important area of research. Hypoxia can exacerbate inflammation via the prolylhydroxylase pathway. Inflammation can also trigger hypoxia by damaging mitochondria and endothelial cells to impair blood flow regulation. We hypothesize t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826859/ https://www.ncbi.nlm.nih.gov/pubmed/30052113 http://dx.doi.org/10.1177/1352458518791683 |