Effects of Lidocaine and Src Inhibition on Metastasis in a Murine Model of Breast Cancer Surgery

Breast cancer recurs in 20% of patients following intended curative resection. In vitro data indicates that amide local anaesthetics, including lidocaine, inhibit cancer cell metastasis by inhibiting the tyrosine kinase enzyme Src. In a murine breast cancer surgery model, systemic lidocaine reduces...

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Detalles Bibliográficos
Autores principales: Wall, Thomas P., Crowley, Peter D., Sherwin, Aislinn, Foley, Andrew G., Buggy, Donal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826872/
https://www.ncbi.nlm.nih.gov/pubmed/31546727
http://dx.doi.org/10.3390/cancers11101414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826872/
https://www.ncbi.nlm.nih.gov/pubmed/31546727
http://dx.doi.org/10.3390/cancers11101414

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