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MPT0G612, a Novel HDAC6 Inhibitor, Induces Apoptosis and Suppresses IFN-γ-Induced Programmed Death-Ligand 1 in Human Colorectal Carcinoma Cells

Colorectal cancer (CRC) is the third most common cancer and the leading cause of cancer-associated death worldwide. Histone deacetylases (HDACs) have been implicated in regulating complex cellular mechanisms to influence tumor biology and immunogenicity in various types of cancer. The potential of s...

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Detalles Bibliográficos
Autores principales: Chen, Mei-Chuan, Lin, Yu-Chen, Liao, Yu-Hsuan, Liou, Jing-Ping, Chen, Chun-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826904/
https://www.ncbi.nlm.nih.gov/pubmed/31652644
http://dx.doi.org/10.3390/cancers11101617