The H3K9 Methylation Writer SETDB1 and Its Reader MPP8 Cooperate to Silence Satellite DNA Repeats in Mouse Embryonic Stem Cells

SETDB1 (SET Domain Bifurcated histone lysine methyltransferase 1) is a key lysine methyltransferase (KMT) required in embryonic stem cells (ESCs), where it silences transposable elements and DNA repeats via histone H3 lysine 9 tri-methylation (H3K9me3), independently of DNA methylation. The H3K9 met...

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Detalles Bibliográficos
Autores principales: Cruz-Tapias, Paola, Robin, Philippe, Pontis, Julien, Del Maestro, Laurence, Ait-Si-Ali, Slimane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826936/
https://www.ncbi.nlm.nih.gov/pubmed/31557926
http://dx.doi.org/10.3390/genes10100750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826936/
https://www.ncbi.nlm.nih.gov/pubmed/31557926
http://dx.doi.org/10.3390/genes10100750

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