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Inhibition of TFF3 Enhances Sensitivity—and Overcomes Acquired Resistance—to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma

Dose-dependent toxicity and acquired resistance are two major challenges limiting the efficacious treatment of mammary carcinoma (MC) with doxorubicin. Herein, we investigated the function of Trefoil Factor 3 (TFF3) in the sensitivity and acquired resistance of estrogen receptor positive (ER+) MC ce...

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Detalles Bibliográficos
Autores principales: Poh, Han Ming, Chiou, Yi Shiou, Chong, Qing Yun, Chen, Ru-Mei, Rangappa, Kanchugarakoppal S., Ma, Lan, Zhu, Tao, Kumar, Alan Prem, Pandey, Vijay, Basappa, Lee, Soo-Chin, Lobie, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826976/
https://www.ncbi.nlm.nih.gov/pubmed/31658702
http://dx.doi.org/10.3390/cancers11101528