PARP1 Co-Regulates EP300–BRG1-Dependent Transcription of Genes Involved in Breast Cancer Cell Proliferation and DNA Repair

BRG1, an active subunit of the SWI/SNF chromatin-remodeling complex, enables the EP300-dependent transcription of proliferation and DNA repair genes from their E2F/CpG-driven promoters in breast cancer cells. In the current study, we show that BRG1–EP300 complexes are accompanied by poly-ADP-ribose...

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Detalles Bibliográficos
Autores principales: Sobczak, Maciej, Pitt, Andrew R., Spickett, Corinne M., Robaszkiewicz, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826995/
https://www.ncbi.nlm.nih.gov/pubmed/31614656
http://dx.doi.org/10.3390/cancers11101539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826995/
https://www.ncbi.nlm.nih.gov/pubmed/31614656
http://dx.doi.org/10.3390/cancers11101539

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