HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1

Therapy of acute myeloid leukemia (AML) is unsatisfactory. Histone deacetylase inhibitors (HDACi) are active against leukemic cells in vitro and in vivo. Clinical data suggest further testing of such epigenetic drugs and to identify mechanisms and markers for their efficacy. Primary and permanent AM...

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Detalles Bibliográficos
Autores principales: Beyer, Mandy, Romanski, Annette, Mustafa, Al-Hassan M., Pons, Miriam, Büchler, Iris, Vogel, Anja, Pautz, Andrea, Sellmer, Andreas, Schneider, Günter, Bug, Gesine, Krämer, Oliver H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826998/
https://www.ncbi.nlm.nih.gov/pubmed/31561534
http://dx.doi.org/10.3390/cancers11101436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826998/
https://www.ncbi.nlm.nih.gov/pubmed/31561534
http://dx.doi.org/10.3390/cancers11101436

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