Gene-Specific Targeting of DNA Methylation in the Mammalian Genome

DNA methylation is the most widely-studied epigenetic modification, playing a critical role in the regulation of gene expression. Dysregulation of DNA methylation is implicated in the pathogenesis of numerous diseases. For example, aberrant DNA methylation in promoter regions of tumor-suppressor gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Urbano, Arthur, Smith, Jim, Weeks, Robert J., Chatterjee, Aniruddha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827012/
https://www.ncbi.nlm.nih.gov/pubmed/31600992
http://dx.doi.org/10.3390/cancers11101515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827012/
https://www.ncbi.nlm.nih.gov/pubmed/31600992
http://dx.doi.org/10.3390/cancers11101515

Ejemplares similares