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Gene-Specific Targeting of DNA Methylation in the Mammalian Genome

DNA methylation is the most widely-studied epigenetic modification, playing a critical role in the regulation of gene expression. Dysregulation of DNA methylation is implicated in the pathogenesis of numerous diseases. For example, aberrant DNA methylation in promoter regions of tumor-suppressor gen...

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Detalles Bibliográficos
Autores principales:	Urbano, Arthur, Smith, Jim, Weeks, Robert J., Chatterjee, Aniruddha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827012/ https://www.ncbi.nlm.nih.gov/pubmed/31600992 http://dx.doi.org/10.3390/cancers11101515

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