Constitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC

Background: management of head and neck squamous cell carcinomas (HNSCC) include anti-Epidermal Growth Factor Receptor (EGFR) antibodies and radiotherapy, but resistance emerges in most patients. RAS mutations lead to primary resistance to EGFR blockade in metastatic colorectal cancer but are infreq...

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Detalles Bibliográficos
Autores principales: Coliat, Pierre, Ramolu, Ludivine, Jégu, Jérémie, Gaiddon, Christian, Jung, Alain C., Pencreach, Erwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827016/
https://www.ncbi.nlm.nih.gov/pubmed/31640284
http://dx.doi.org/10.3390/cancers11101607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827016/
https://www.ncbi.nlm.nih.gov/pubmed/31640284
http://dx.doi.org/10.3390/cancers11101607

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