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Constitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC

Background: management of head and neck squamous cell carcinomas (HNSCC) include anti-Epidermal Growth Factor Receptor (EGFR) antibodies and radiotherapy, but resistance emerges in most patients. RAS mutations lead to primary resistance to EGFR blockade in metastatic colorectal cancer but are infreq...

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Detalles Bibliográficos
Autores principales:	Coliat, Pierre, Ramolu, Ludivine, Jégu, Jérémie, Gaiddon, Christian, Jung, Alain C., Pencreach, Erwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827016/ https://www.ncbi.nlm.nih.gov/pubmed/31640284 http://dx.doi.org/10.3390/cancers11101607

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