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Understanding the Interplay between COX-2 and hTERT in Colorectal Cancer Using a Multi-Omics Analysis

Background: Cyclooxygenase 2 (COX-2) is involved in the initial steps of colorectal cancer (CRC) formation, playing a key role in the catalysis of arachidonic acid to prostaglandin E2 (PGE(2)). The human telomerase reverse transcriptase (hTERT or TERT) also plays an important role in colorectal canc...

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Detalles Bibliográficos
Autores principales: Ayiomamitis, Georgios D., Notas, George, Vasilakaki, Thivi, Tsavari, Aikaterini, Vederaki, Styliani, Theodosopoulos, Theodosis, Kouroumalis, Elias, Zaravinos, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827032/
https://www.ncbi.nlm.nih.gov/pubmed/31614548
http://dx.doi.org/10.3390/cancers11101536