An IKK/NF-κB Activation/p53 Deletion Sequence Drives Liver Carcinogenesis and Tumor Differentiation

Background: Most liver tumors arise on the basis of chronic liver diseases that trigger inflammatory responses. Besides inflammation, subsequent defects in the p53-signaling pathway frequently occurs in liver cancer. In this study, we analyzed the consequences of inflammation and p53 loss in liver c...

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Detalles Bibliográficos
Autores principales: Svinarenko, Michael, Katz, Sarah-Fee, Tharehalli, Umesh, Mulaw, Medhanie A., Maier, Harald J., Sunami, Yoshiaki, Fischer, Sarah K., Chen, Yuexin, Heurich, Sabine, Erkert, Lena, Tannapfel, Andrea, Wirth, Thomas, Schirmbeck, Reinhold, Seufferlein, Thomas, Lechel, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827060/
https://www.ncbi.nlm.nih.gov/pubmed/31546614
http://dx.doi.org/10.3390/cancers11101410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827060/
https://www.ncbi.nlm.nih.gov/pubmed/31546614
http://dx.doi.org/10.3390/cancers11101410

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