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An IKK/NF-κB Activation/p53 Deletion Sequence Drives Liver Carcinogenesis and Tumor Differentiation
Background: Most liver tumors arise on the basis of chronic liver diseases that trigger inflammatory responses. Besides inflammation, subsequent defects in the p53-signaling pathway frequently occurs in liver cancer. In this study, we analyzed the consequences of inflammation and p53 loss in liver c...
Autores principales: | Svinarenko, Michael, Katz, Sarah-Fee, Tharehalli, Umesh, Mulaw, Medhanie A., Maier, Harald J., Sunami, Yoshiaki, Fischer, Sarah K., Chen, Yuexin, Heurich, Sabine, Erkert, Lena, Tannapfel, Andrea, Wirth, Thomas, Schirmbeck, Reinhold, Seufferlein, Thomas, Lechel, André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827060/ https://www.ncbi.nlm.nih.gov/pubmed/31546614 http://dx.doi.org/10.3390/cancers11101410 |
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