Hepatic Stress Response in HCV Infection Promotes STAT3-Mediated Inhibition of HNF4A-miR-122 Feedback Loop in Liver Fibrosis and Cancer Progression

Hepatitis C virus (HCV) infection compromises the natural defense mechanisms of the liver leading to a progressive end stage disease such as cirrhosis and hepatocellular carcinoma (HCC). The hepatic stress response generated due to viral replication in the endoplasmic reticulum (ER) undergoes a step...

Descripción completa

Detalles Bibliográficos
Autores principales: Aydin, Yucel, Kurt, Ramazan, Song, Kyoungsub, Lin, Dong, Osman, Hanadi, Youngquist, Brady, Scott, John W., Shores, Nathan J., Thevenot, Paul, Cohen, Ari, Dash, Srikanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827087/
https://www.ncbi.nlm.nih.gov/pubmed/31547152
http://dx.doi.org/10.3390/cancers11101407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827087/
https://www.ncbi.nlm.nih.gov/pubmed/31547152
http://dx.doi.org/10.3390/cancers11101407

Ejemplares similares