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Hepatic Stress Response in HCV Infection Promotes STAT3-Mediated Inhibition of HNF4A-miR-122 Feedback Loop in Liver Fibrosis and Cancer Progression
Hepatitis C virus (HCV) infection compromises the natural defense mechanisms of the liver leading to a progressive end stage disease such as cirrhosis and hepatocellular carcinoma (HCC). The hepatic stress response generated due to viral replication in the endoplasmic reticulum (ER) undergoes a step...
Autores principales: | Aydin, Yucel, Kurt, Ramazan, Song, Kyoungsub, Lin, Dong, Osman, Hanadi, Youngquist, Brady, Scott, John W., Shores, Nathan J., Thevenot, Paul, Cohen, Ari, Dash, Srikanta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827087/ https://www.ncbi.nlm.nih.gov/pubmed/31547152 http://dx.doi.org/10.3390/cancers11101407 |
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