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Epigenetic Drugs for Cancer and microRNAs: A Focus on Histone Deacetylase Inhibitors

Over recent decades, it has become clear that epigenetic abnormalities are involved in the hallmarks of cancer. Histone modifications, such as acetylation, play a crucial role in cancer development and progression, by regulating gene expression, such as for oncogenes or tumor suppressor genes. There...

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Detalles Bibliográficos
Autores principales: Autin, Pierre, Blanquart, Christophe, Fradin, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827107/
https://www.ncbi.nlm.nih.gov/pubmed/31658720
http://dx.doi.org/10.3390/cancers11101530