RAD52 as a Potential Target for Synthetic Lethality-Based Anticancer Therapies

Alterations in DNA repair systems play a key role in the induction and progression of cancer. Tumor-specific defects in DNA repair mechanisms and activation of alternative repair routes create the opportunity to employ a phenomenon called “synthetic lethality” to eliminate cancer cells. Targeting th...

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Detalles Bibliográficos
Autores principales: Toma, Monika, Sullivan-Reed, Katherine, Śliwiński, Tomasz, Skorski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827130/
https://www.ncbi.nlm.nih.gov/pubmed/31615159
http://dx.doi.org/10.3390/cancers11101561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827130/
https://www.ncbi.nlm.nih.gov/pubmed/31615159
http://dx.doi.org/10.3390/cancers11101561

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