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DNA Methylation of Enhancer Elements in Myeloid Neoplasms: Think Outside the Promoters?

Gene regulation through DNA methylation is a well described phenomenon that has a prominent role in physiological and pathological cell-states. This epigenetic modification is usually grouped in regions denominated CpG islands, which frequently co-localize with gene promoters, silencing the transcri...

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Detalles Bibliográficos
Autores principales: Ordoñez, Raquel, Martínez-Calle, Nicolás, Agirre, Xabier, Prosper, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827153/
https://www.ncbi.nlm.nih.gov/pubmed/31554341
http://dx.doi.org/10.3390/cancers11101424