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DNA Methylation of Enhancer Elements in Myeloid Neoplasms: Think Outside the Promoters?
Gene regulation through DNA methylation is a well described phenomenon that has a prominent role in physiological and pathological cell-states. This epigenetic modification is usually grouped in regions denominated CpG islands, which frequently co-localize with gene promoters, silencing the transcri...
Autores principales: | Ordoñez, Raquel, Martínez-Calle, Nicolás, Agirre, Xabier, Prosper, Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827153/ https://www.ncbi.nlm.nih.gov/pubmed/31554341 http://dx.doi.org/10.3390/cancers11101424 |
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