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Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma

Malignant pleural mesothelioma (MPM) is a lethal cancer with limited treatment options. No targeted therapy has emerged yet. Here, we performed an integrated molecular characterization of patient tumors in the TCGA dataset, and discovered that endoplasmic reticulum (ER) stress and the adaptive unfol...

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Detalles Bibliográficos
Autores principales: Xu, Duo, Yang, Haitang, Yang, Zhang, Berezowska, Sabina, Gao, Yanyun, Liang, Shun-Qing, Marti, Thomas M., Hall, Sean R. R., Dorn, Patrick, Kocher, Gregor J., Schmid, Ralph A., Peng, Ren-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827154/
https://www.ncbi.nlm.nih.gov/pubmed/31597321
http://dx.doi.org/10.3390/cancers11101502