Predictive modelling using pathway scores: robustness and significance of pathway collections

BACKGROUND: Transcriptomic data is often used to build statistical models which are predictive of a given phenotype, such as disease status. Genes work together in pathways and it is widely thought that pathway representations will be more robust to noise in the gene expression levels. We aimed to t...

Descripción completa

Detalles Bibliográficos
Autores principales: Segura-Lepe, Marcelo P., Keun, Hector C., Ebbels, Timothy M. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827178/
https://www.ncbi.nlm.nih.gov/pubmed/31684857
http://dx.doi.org/10.1186/s12859-019-3163-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827178/
https://www.ncbi.nlm.nih.gov/pubmed/31684857
http://dx.doi.org/10.1186/s12859-019-3163-0

Ejemplares similares