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Predictive modelling using pathway scores: robustness and significance of pathway collections
BACKGROUND: Transcriptomic data is often used to build statistical models which are predictive of a given phenotype, such as disease status. Genes work together in pathways and it is widely thought that pathway representations will be more robust to noise in the gene expression levels. We aimed to t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827178/ https://www.ncbi.nlm.nih.gov/pubmed/31684857 http://dx.doi.org/10.1186/s12859-019-3163-0 |