Lower serum expression of miR-181c-5p is associated with increased plasma levels of amyloid-beta 1–40 and cerebral vulnerability in normal aging

BACKGROUND: Previous studies have shown that expression levels of miR-181c are downregulated by amyloid-β (Aβ) deposition and chronic cerebral hypoperfusion, both factors largely associated with the development of AD. Moreover, reduced 2-[18F]fluoro-2-deoxy-D-glucose (FDG)-PET brain metabolism and v...

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Detalles Bibliográficos
Autores principales: Manzano-Crespo, Marta, Atienza, Mercedes, Cantero, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827222/
https://www.ncbi.nlm.nih.gov/pubmed/31700619
http://dx.doi.org/10.1186/s40035-019-0174-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827222/
https://www.ncbi.nlm.nih.gov/pubmed/31700619
http://dx.doi.org/10.1186/s40035-019-0174-8

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