Cargando…

Human cardiac myosin–binding protein C restricts actin structural dynamics in a cooperative and phosphorylation-sensitive manner

Cardiac myosin–binding protein C (cMyBP-C) is a thick filament-associated protein that influences actin-myosin interactions. cMyBP-C alters myofilament structure and contractile properties in a protein kinase A (PKA) phosphorylation-dependent manner. To determine the effects of cMyBP-C and its phosp...

Descripción completa

Detalles Bibliográficos
Autores principales: Bunch, Thomas A., Kanassatega, Rhye-Samuel, Lepak, Victoria C., Colson, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827302/
https://www.ncbi.nlm.nih.gov/pubmed/31519753
http://dx.doi.org/10.1074/jbc.RA119.009543