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Human cardiac myosin–binding protein C restricts actin structural dynamics in a cooperative and phosphorylation-sensitive manner
Cardiac myosin–binding protein C (cMyBP-C) is a thick filament-associated protein that influences actin-myosin interactions. cMyBP-C alters myofilament structure and contractile properties in a protein kinase A (PKA) phosphorylation-dependent manner. To determine the effects of cMyBP-C and its phosp...
Autores principales: | Bunch, Thomas A., Kanassatega, Rhye-Samuel, Lepak, Victoria C., Colson, Brett A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827302/ https://www.ncbi.nlm.nih.gov/pubmed/31519753 http://dx.doi.org/10.1074/jbc.RA119.009543 |
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