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Genomic tagging of endogenous human ESCRT-I complex preserves ESCRT-mediated membrane-remodeling functions

The endosomal sorting complexes required for transport (ESCRT) machinery drives membrane scission for diverse cellular functions that require budding away from the cytosol, including cell division and transmembrane receptor trafficking and degradation. The ESCRT machinery is also hijacked by retrovi...

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Detalles Bibliográficos
Autores principales: Hoffman, Huxley K., Fernandez, Melissa V., Groves, Nicholas S., Freed, Eric O., van Engelenburg, Schuyler B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827313/
https://www.ncbi.nlm.nih.gov/pubmed/31519756
http://dx.doi.org/10.1074/jbc.RA119.009372