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Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway

Carcinogenesis of the small intestine is rare in humans and rodents. Oral exposure to hexavalent chromium (Cr(VI)) and the fungicides captan and folpet induce intestinal carcinogenesis in mice. Previously (Toxicol Pathol. 330:48-52), we showed that B6C3F1 mice exposed to carcinogenic concentrations...

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Detalles Bibliográficos
Autores principales: Chappell, Grace A., Rager, Julia E., Wolf, Jeffrey, Babic, Milos, LeBlanc, Kyle J., Ring, Caroline L., Harris, Mark A., Thompson, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827348/
https://www.ncbi.nlm.nih.gov/pubmed/31558096
http://dx.doi.org/10.1177/0192623319873882