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Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules

Vasa homologs are ATP-dependent DEAD-box helicases, multipotency factors, and critical components that specify and protect the germline. They regulate translation, amplify piwi-interacting RNAs (piRNAs), and act as RNA solvents; however, the limited availability of mutagenesis-derived alleles and th...

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Detalles Bibliográficos
Autores principales: Marnik, Elisabeth A., Fuqua, J. Heath, Sharp, Catherine S., Rochester, Jesse D., Xu, Emily L., Holbrook, Sarah E., Updike, Dustin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827368/
https://www.ncbi.nlm.nih.gov/pubmed/31506335
http://dx.doi.org/10.1534/genetics.119.302670