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Diverse DNA Sequence Motifs Activate Meiotic Recombination Hotspots Through a Common Chromatin Remodeling Pathway

In meiosis, multiple different DNA sequence motifs help to position homologous recombination at hotspots in the genome. How do the seemingly disparate cis-acting regulatory modules each promote locally the activity of the basal recombination machinery? We defined molecular mechanisms of action for f...

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Detalles Bibliográficos
Autores principales: Mukiza, Tresor O., Protacio, Reine U., Davidson, Mari K., Steiner, Walter W., Wahls, Wayne P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827382/
https://www.ncbi.nlm.nih.gov/pubmed/31511300
http://dx.doi.org/10.1534/genetics.119.302679