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Unresolved Recombination Intermediates Cause a RAD9-Dependent Cell Cycle Arrest in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the conserved Sgs1-Top3-Rmi1 helicase-decatenase regulates homologous recombination by limiting accumulation of recombination intermediates that are crossover precursors. In vitro studies have suggested that this may be due to dissolution of double-Holliday junction join...

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Detalles Bibliográficos
Autores principales: Kaur, Hardeep, GN, Krishnaprasad, Lichten, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827386/
https://www.ncbi.nlm.nih.gov/pubmed/31562181
http://dx.doi.org/10.1534/genetics.119.302632