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Pertuzumab in the treatment of HER2-positive breast cancer: an evidence-based review of its safety, efficacy, and place in therapy

Human epidermal growth factor receptor 2 (HER2)-positive breast cancer is a distinct subset of breast cancer that results from overexpression of HER2 protein. Pertuzumab—a recombinant humanized monoclonal antibody that binds to the extracellular dimerization domain II of HER2—was recently approved f...

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Detalles Bibliográficos
Autores principales: Ishii, Kei, Morii, Nao, Yamashiro, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827570/
https://www.ncbi.nlm.nih.gov/pubmed/31802990
http://dx.doi.org/10.2147/CE.S217848