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Effects of α-lipoic acid on LPS-induced neuroinflammation and NLRP3 inflammasome activation through the regulation of BV-2 microglial cells activation

Microglial cells are known as the main immune cells in the central nervous system, both regulating its immune response and maintaining its homeostasis. Furthermore, the antioxidant α-lipoic acid (LA) is a recognized therapeutic drug for diabetes because it can easily invade the blood–brain barrier....

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Detalles Bibliográficos
Autores principales: Kim, Su Min, Ha, Ji Sun, Han, A Reum, Cho, Sung-Woo, Yang, Seung-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827572/
https://www.ncbi.nlm.nih.gov/pubmed/30940325
http://dx.doi.org/10.5483/BMBRep.2019.52.10.026