Differential regulatory network-based quantification and prioritization of key genes underlying cancer drug resistance based on time-course RNA-seq data

Drug resistance is a major cause for the failure of cancer chemotherapy or targeted therapy. However, the molecular regulatory mechanisms controlling the dynamic evolvement of drug resistance remain poorly understood. Thus, it is important to develop methods for identifying key gene regulatory mecha...

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Detalles Bibliográficos
Autores principales: Zhang, Jiajun, Zhu, Wenbo, Wang, Qianliang, Gu, Jiayu, Huang, L. Frank, Sun, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827891/
https://www.ncbi.nlm.nih.gov/pubmed/31682596
http://dx.doi.org/10.1371/journal.pcbi.1007435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827891/
https://www.ncbi.nlm.nih.gov/pubmed/31682596
http://dx.doi.org/10.1371/journal.pcbi.1007435

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