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Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis

Liposomes containing phosphatidylserine (PS) has been used for the delivery of drugs into the intramacrophage milieu. Leishmania (L.) infantum parasites live inside macrophages and cause a fatal and neglected viscerotropic disease, with a toxic treatment. Sertraline was studied as a free formulation...

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Detalles Bibliográficos
Autores principales: Romanelli, Maiara Maria, da Costa-Silva, Thais Alves, Cunha-Junior, Edezio, Dias Ferreira, Daiane, Guerra, Juliana M., Galisteo, Andres Jimenez, Pinto, Erika Gracielle, Barbosa, Leandro R. S., Torres-Santos, Eduardo Caio, Tempone, Andre Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828611/
https://www.ncbi.nlm.nih.gov/pubmed/31737574
http://dx.doi.org/10.3389/fcimb.2019.00353